Mrs. King is co-founder and CEO of GlycoMimetics, Inc. (GMI). Before founding GMI, she was an Executive in Residence at New Enterprise Associates (NEA), one of the nation’s leading venture capital firms. Mrs. King came to NEA after serving as a senior vice president of Novartis Corporation. Before joining Novartis, Mrs. King spent 10 years with Genetic Therapy, Inc. through the company’s early stage, initial public offering and eventual sale to Novartis. After the sale to Novartis, she was named CEO and ran the company as a wholly-owned subsidiary of Novartis. Mrs. King also worked previously at ALZA Corporation in Palo Alto, CA and at Bain & Company in Boston. Mrs. King is the past Chair of the Board as well as past of the Chair Emerging Companies Governing Board of the Biotechnology Innovation Organization (“BIO”); she continues to serve on BIO’s executive committee. She also served as Chair of the Maryland Life Sciences Advisory Board under former Governor Martin O’Malley. Ms. King now serves on the boards of Novavax, Inc. and the University of Maryland BioPark. She received her B.A. degree from Dartmouth College and her M.B.A. from Harvard Business School.
John Magnani — Ph.D. Senior Vice President, Research, and Chief Scientific Officer
Dr. Magnani is co-founder and CSO of GlycoMimetics, Inc (GMI). Prior to co-founding GMI, Dr. Magnani founded and led a predecessor company, GlycoTech Corporation, as its President and CEO. Previously, he helped co-found the U.S. subsidiary of BioCarb and became its international Vice President of Research. Dr. Magnani received his Ph.D. from Princeton University and then joined the Laboratory of Biological Pharmacology of the National Institute of Arthritis, Diabetes and Digestive and Kidney Diseases (NIADDK) of the National Institutes of Health (NIH). He remained at the NIH for 10 years, finally serving as a tenured research chemist. Dr. Magnani is an expert in glycobiology, having discovered and characterized many carbohydrate tumor antigens, such as the FDA-approved cancer diagnostic, CA19-9. He also developed fundamental technology for the identification of functional carbohydrate epitopes. Dr. Magnani is the discoverer of Sialyl Lea and its functions. He was the first to identify the binding domain to the selectins common to both Sialyl Lea and Sialyl Lex and used this information to develop potent selectin antagonists as drug candidates now in clinical trials. He is the recipient of the 2015 President’s Innovation Award from the Society of Glycobiology, has authored over 100 scientific publications and is an inventor on more than 90 issued patents.
Helen Thackray, M.D., FAAP — Senior Vice President, Clinical Development, and Chief Medical Officer
Dr. Thackray joined GlycoMimetics in 2006. She has extensive leadership experience in design and execution of development programs for rare diseases, including Orphan and Fast Track products. At GlycoMimetics, she oversees development of investigational products for the company, including clinical development programs in sickle cell disease, AML, multiple myeloma, other cancers and thrombosis. Dr. Thackray is board-certified and an assistant clinical professor of pediatrics at the George Washington University School of Medicine. Previously, she was vice president of clinical product development at Biosynexus, Inc. She served as pediatric chief resident at Children’s National Medical Center, as a medical genetics fellow at the National Human Genome Research Institute of the National Institutes of Health, as a member of the Institutional Review Board of the National Center for Healthcare Statistics, and is a fellow of the American Academy of Pediatrics. She now serves on the ICH E11A Expert Working Group for the development of a harmonized guideline for pediatric extrapolation in drug development. Dr. Thackray received her B.S. from Stanford University and her M.D. from George Washington University School of Medicine.
Brian Hahn — Chief Financial Officer
Mr. Hahn has more than 15 years of senior financial and operations experience in emerging organizations. He joined GlycoMimetics in 2010. Previously, Mr. Hahn served as executive director of finance at MiddleBrook Pharmaceuticals (formerly Advancis Pharmaceutical), a publicly-traded specialty pharmaceutical company. Prior to Advancis, he was a senior accountant with Bering Truck Corporation. During the last 10 years, Mr. Hahn has worked with life science companies from early stages through product launch. He has been involved in multiple initial public offerings and has broad experience in developing strategic plans, creating business models, establishing accounting and auditing systems and ensuring Sarbanes-Oxley compliance. Currently, Mr. Hahn serves as co-chairman of the BIO Finance and Tax Committee, as a co-chairman of the Steering Committee of the Washington, DC chapter of the Association for Bio Financial Officers (ABFO), and also serves on the Securities and Exchange Commissions’ Advisory Committee on Small and Emerging Companies. He received a B.B.A. in Accounting from Shenandoah University and an M.B.A. from the University of Maryland.
Armand Girard — Vice President, Corporate Development
Mr. Girard has extensive partnering experience, including the completion of collaborations, licenses, acquisitions and spinouts by and between leading pharmaceutical and biotech companies. As the GlycoMimetics Vice President of Corporate Development, he is responsible for corporate strategy, pursuing partnering and licensing opportunities in support of the GlycoMimetics pipeline and for managing the company's corporate and institutional alliances. Prior to joining GlycoMimetics, Mr. Girard held the positions of vice president for technical assessment and senior director for business development at Shire Pharmaceuticals. He has more than 20 years of business development, research and development and project management experience in life sciences for companies including Strakan Life Sciences, Pro-Virus, Inc. and Otsuka Pharmaceuticals. Mr. Girard holds an M.B.A. from St. Joseph's University Haub School of Business and a B.A. from Lehigh University.
Henry Flanner — Vice President, Technical Operations
Mr. Flanner has more than 20 years of experience in the development of biopharmaceutical products in emerging pharmaceutical companies. He joined GlycoMimetics in 2007, bringing knowledge and experience in chemistry, manufacturing and controls (CMC) and biopharmaceutics. At GlycoMimetics, he oversees the scale-up and optimization of manufacturing processes for production of clinical supplies. He also manages the non-clinical toxicology and pharmacokinetics programs for the company. Prior to joining GlycoMimetics, Mr. Flanner was senior director of pharmaceutical research at MiddleBrook Pharmaceuticals, and director of drug delivery sciences at Shire Laboratories. He holds over 20 formulation patents and co-developed the in vitro dissolution profile comparison factors, f1 and f2, cited in multiple regulatory guidances. He received a B.S. in Chemical Engineering from the University of South Carolina, and an M.S. in Chemical Engineering from Johns Hopkins University.
Eddie Li, Ph.D. — Vice President, Regulatory Affairs
Dr. Li joined GlycoMimetics in 2018, bringing with him more than 20 years of experience in global regulatory strategies for development programs as well as marketed products in oncology, hematology, cardiovascular, diabetes/metabolism, neurology, inflammation and rare diseases. His extensive regulatory background and achievements for Lovenox, and his continued passion for the pharmacology, CMC and diverse therapeutic potentials of glycomimetic-based compounds, is also particularly compatible with GlycoMimetics’ R&D platform and business strategies. Previously, he worked for several biopharmaceutical companies including AstraZeneca, J&J’s McNeil Consumer and Specialty Pharma, Sanofi and, most recently, Indivior in progressing roles ranging from Global Regulatory Leader, Global Regulatory Therapeutic Area Head to Senior Vice President of Global Regulatory Affairs. He also worked at the US Food and Drug Administration’s (FDA) Center for Drug Evaluation and Research as a staff reviewer. Dr. Li received a medical degree from Shanghai First Medical College and a Ph.D. in toxicology from University of Arkansas. He completed his postdoctoral training at FDA’s National Center for Toxicology Research and the Massachusetts Institute of Technology.
Margot Mongold — Vice President, Human Resources
Mrs. Mongold joined GlycoMimetics in 2018 with more than 20 years of experience in Human Resources Management within the biopharmaceutical industry. At GlycoMimetics, she leads human resource functions, including leadership development, organizational design, staffing and recruitment, and compensation strategies. Prior to joining the company, she had a consulting practice that focused on early-stage through maturing companies with clients in the U.S., Europe, and Australia. Mrs. Mongold was the head of Human Resources for GenVec, Inc. and was the Senior Director, Human Resources at EntreMed, Inc. for five years. She also led the Human Resources function for Genetic Therapy, Inc. for five years. Mrs. Mongold earned a B.A. in Psychology and Sociology from American University and received her M.A. in Human Resource Management from George Washington University. She is certified in Myers–Briggs Type Indicator and Frontline Leadership. She is an active member of the Society for Human Resources Management.